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Tõre Vallutaja viha polymerase kappa inhibitor jahvatatud sügavus tofu

Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity | HTML
Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity | HTML

RCSB PDB - 3PZP: Human DNA polymerase kappa extending opposite a cis-syn thymine dimer
RCSB PDB - 3PZP: Human DNA polymerase kappa extending opposite a cis-syn thymine dimer

Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy?
Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy?

Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer | Molecular Biosciences
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer | Molecular Biosciences

Translesion DNA Synthesis and Carcinogenesis | SpringerLink
Translesion DNA Synthesis and Carcinogenesis | SpringerLink

DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library

Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis - ScienceDirect
Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis - ScienceDirect

Example of an indirect mechanism mediated by curcumin. Adapted from... | Download Scientific Diagram
Example of an indirect mechanism mediated by curcumin. Adapted from... | Download Scientific Diagram

Genome-wide Identification of Structure-Forming Repeats as Principal Sites of Fork Collapse upon ATR Inhibition - ScienceDirect
Genome-wide Identification of Structure-Forming Repeats as Principal Sites of Fork Collapse upon ATR Inhibition - ScienceDirect

Frontiers | Early Drug Discovery and Development of Novel Cancer Therapeutics Targeting DNA Polymerase Eta (POLH) | Oncology
Frontiers | Early Drug Discovery and Development of Novel Cancer Therapeutics Targeting DNA Polymerase Eta (POLH) | Oncology

Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife

Human DNA polymerase α in binary complex with a DNA:DNA template-primer | Scientific Reports
Human DNA polymerase α in binary complex with a DNA:DNA template-primer | Scientific Reports

Genes | Free Full-Text | Maintenance of Genome Integrity: How Mammalian Cells Orchestrate Genome Duplication by Coordinating Replicative and Specialized DNA Polymerases | HTML
Genes | Free Full-Text | Maintenance of Genome Integrity: How Mammalian Cells Orchestrate Genome Duplication by Coordinating Replicative and Specialized DNA Polymerases | HTML

Translesion synthesis DNA polymerase η exhibits a specific RNA extension activity and a transcription-associated function | Scientific Reports
Translesion synthesis DNA polymerase η exhibits a specific RNA extension activity and a transcription-associated function | Scientific Reports

Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity | HTML
Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity | HTML

Translesion DNA synthesis in the context of cancer research | Cancer Cell International | Full Text
Translesion DNA synthesis in the context of cancer research | Cancer Cell International | Full Text

DNA polymerases and cancer | Nature Reviews Cancer
DNA polymerases and cancer | Nature Reviews Cancer

Unravelling roles of error-prone DNA polymerases in shaping cancer genomes | Oncogene
Unravelling roles of error-prone DNA polymerases in shaping cancer genomes | Oncogene

RCSB PDB - 5T14: DNA polymerase kappa extending beyond a bulky major benzo[a]pyrene adduct
RCSB PDB - 5T14: DNA polymerase kappa extending beyond a bulky major benzo[a]pyrene adduct

The Proliferating Cell Nuclear Antigen (PCNA)-interacting Protein (PIP) Motif of DNA Polymerase η Mediates Its Interaction with the C-terminal Domain of Rev1* - Journal of Biological Chemistry
The Proliferating Cell Nuclear Antigen (PCNA)-interacting Protein (PIP) Motif of DNA Polymerase η Mediates Its Interaction with the C-terminal Domain of Rev1* - Journal of Biological Chemistry

DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library

DNA polymerase κ: Friend or foe?
DNA polymerase κ: Friend or foe?

Mechanistic map of the effect of TNF and GCs on MCF7 cells.... | Download Scientific Diagram
Mechanistic map of the effect of TNF and GCs on MCF7 cells.... | Download Scientific Diagram

Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife

Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender - ScienceDirect
Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender - ScienceDirect